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Fentanyl and various opioids are the major cause of the spike in overdose deaths in the U.S in the last 2 a long time. Two milligrams of fentanyl, that's such as a handful of grains, is considered a fatal dose.four A fentanyl overdose could be fatal.There are two types of fentanyl - pharmaceutical fentanyl and illegally made fentanyl. Both varietie